Helix Tech Stack

Genomic data platform for health systems and life sciences companies

Hospitals and Health Care San Mateo, California 51–200 employees Founded 2015 Privately Held

Helix operates a population genomics platform that ingests, processes, and surfaces genomic data for clinical care and drug development. The tech stack—Snowflake, AWS, Python, Go, and a mature observability layer (Datadog, PagerDuty)—reflects a data-heavy, infrastructure-first organization. Active projects centered on cloud migration, CI/CD maturity, and clinico-genomic dataset construction signal a company transitioning from research infrastructure toward scaled operational delivery for health systems and payers.

Tech Stack 40 technologies

Core StackSnowflake AWS GitHub Copilot OpenAI Tableau Thoughtspot HubSpot JavaScript Go Python Java React Terraform Datadog PagerDuty Next.js TypeScript Claude Gemini Google Workspace macOS AWS CDK Udemy Automox PowerShell Jira Service Desk Duo Security LDAP PRTG Network Monitor Tenable.io+10 more

AdoptingAWS

What Helix Is Building

◆Challenges

Optimizing cloud spending
Accelerating integration of genomic data into clinical practice
Cloud migration of lab systems
Incident response management
Security and authentication system issues
Starting diagnostics journey
Market penetration
Expanding market opportunities
Improving website performance
Integrating marketing platforms

▲Active Projects

Cloud infrastructure evolution
Ci/cd pipeline development
Observability strategy implementation
Software platform for providers and health system partners
Building clinico-genomic dataset for partners
Designing data processing pipelines for clinical and genomic datasets
Migrating monitoring and storage to aws
Deploying operational dashboards in datadog
Automating system management with automox and powershell
Building new diagnostic tests

Hiring Activity

Decelerating10 roles · 3 in 30d

Department

Engineering

Ops

Data

Healthcare

Marketing

Seniority

Senior

Manager

Mid

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About Helix

Helix builds a precision health platform that helps health systems, life sciences companies, and payers integrate genomic data into patient care workflows and therapeutic development. Founded in 2015 and based in San Mateo, the company operates a next-generation sequencing (NGS) and bioinformatics operation that processes population-scale genomic datasets. Work spans NGS test development, exome sequencing, bioinformatic analysis, and the clinical integration layer—moving raw genomic data through processing pipelines into actionable diagnostics and population health insights. The organization is lean (51–200 employees) with a senior-heavy engineering and ops focus, currently navigating cloud infrastructure modernization and diagnostic product expansion.

HeadquartersSan Mateo, California

Company Size51–200 employees

Founded2015

Hiring MarketsMexico, United States

Frequently Asked Questions

What tech stack does Helix use?

Helix runs Snowflake, AWS, Python, Go, Java, and React for core systems. Observability is handled by Datadog and PagerDuty. They also use GitHub Copilot and Claude for development, and Tableau/Thoughtspot for analytics.

What is Helix working on?

Active projects include cloud infrastructure evolution and AWS migration, CI/CD pipeline development, observability strategy (Datalog deployments), software platforms for provider partners, clinico-genomic dataset construction, and new diagnostic test development.