Clinical-stage oncology biologics: bispecific, trispecific antibodies and ADCs
SystImmune develops multi-specific antibodies and ADCs for solid tumors, pairing a classic clinical-pharmacology stack (SAS, CDISC, NONMEM, WinNonlin, Spotfire) with an AI protein-design toolkit (AlphaFold, ProteinMPNN, GROMACS, Llama, LangChain, Milvus, Ray). Senior- and director-heavy research hiring, plus a Chief Commercial Officer search and NDA/BLA submission work, points to a push from clinical stage toward commercialization.
Notable leadership hires: Analytical Director, Chief Commercial Officer
SystImmune is a privately held biopharmaceutical company founded in 2014 and headquartered in Bothell, WA. It develops antibody-based cancer therapies, including bispecific and trispecific antibodies and antibody-drug conjugates, designed to act on the solid tumor microenvironment by attacking tumors directly or engaging the immune system. The company employs 51–200 people and hires in the United States. Its work spans discovery research, protein engineering, analytical development and clinical trial operations, supported by business systems such as NetSuite and Concur.
SystImmune uses SAS, CDISC, Spotfire, NONMEM and WinNonlin for clinical and PK analysis, AlphaFold, ProteinMPNN and GROMACS for protein design, plus Python, Ray, Dask, AWS, LIMS and NetSuite.
Yes. Hiring is accelerating and centers on research roles, with data, clinical and healthcare positions plus leadership searches including an Analytical Director and Chief Commercial Officer, all in the United States.
Current work includes clinical trial implementation, NDA/BLA regulatory submissions, companion diagnostic IHC development across oncology programs, a cell-free expression platform and display-based protein engineering.
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SystImmune's technology stack, projects, and hiring signals are inferred from public hiring and company data — career pages, public listings, and company web presence — then clustered and de-duplicated. Figures are estimates that refresh over time. Read our full methodology →
This is not an official vendor or customer list. It is a technology-adoption signal inferred from public data, intended for B2B research.