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Personalis, Inc. Tech Stack

Ultrasensitive cell-free DNA testing for cancer detection and monitoring

Biotechnology Research Fremont, California 201–500 employees Founded 2011 Public Company

Personalis develops circulating tumor DNA (ctDNA) assays for detecting minimal residual disease and cancer recurrence. The tech stack reveals a biotech operations platform: LIMS and QAD for lab workflow and manufacturing, Salesforce + Tableau for commercial execution, and specialized genomics tools (qPCR, Qubit, TapeStation). Hiring is balanced across healthcare, ops, research, and data—reflecting simultaneous pressure to scale production (reagent manufacturing, GMP compliance, quality control) while advancing assay science (MRD detection, cell-free platform development).

Tech Stack 46 technologies

Core StackSalesforce Tableau Power BI Python Java AWS VMware Active Directory GitLab ADP QAD LIMS Service Cloud Cisco Nexus Cisco Meraki Dell VxRail VAST Data Dell Isilon GCP AWS Direct Connect Red Hat Enterprise Linux Ubuntu CentOS TapeStation Qubit qPCR ADP Workforce Now macOS Jamf Google Meet+16 more

What Personalis, Inc. Is Building

Challenges

  • Quality control failures
  • Expanding assay capabilities
  • Engaging key opinion leaders
  • Scaling up production processes
  • Ensuring compliance with iso 13485/gmp
  • Cost-effective production
  • Developing novel cell-free technologies
  • Reducing turnaround time
  • Adoption of novel ctdna technologies
  • Improving lab process efficiency

Active Projects

  • Next personal mrd assay
  • Assay development
  • Quality management
  • Collaborate with commercial alliance partners
  • Proof of principle projects
  • Key opinion leader engagement
  • Clinical advocacy & education
  • Cell-free platform development
  • Scale-up of reagent manufacturing processes
  • Technology transfer of new product introduction

Hiring Activity

Accelerating30 roles · 15 in 30d

Department

Healthcare
5
Ops
5
Research
5
Data
3
Engineering
3
Support
2
Finance
1
Manufacturing
1

Seniority

Mid
12
Senior
12
Junior
3
Director
2
Staff
1

Notable leadership hires: Advanced Technologies Director

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About Personalis, Inc.

Personalis is a public biotech company focused on personalized cancer management through genomic profiling and minimal residual disease detection. The platform combines tumor-and-normal DNA analysis with proprietary algorithms to guide treatment selection and monitor disease evolution over time. Products serve oncologists and drug developers seeking earlier detection, more comprehensive mutation profiling, and biomarker insights for clinical trials. The company operates a vertically integrated model spanning assay development, lab operations, manufacturing, and commercial partnerships—evident in active projects around reagent scale-up, quality management, and key opinion leader engagement.

HeadquartersFremont, California
Company Size201–500 employees
Founded2011
Hiring MarketsUnited States

Frequently Asked Questions

What technology does Personalis use for testing?

Personalis uses next-generation sequencing (NGS) infrastructure including qPCR, Qubit, and TapeStation for sample analysis, paired with LIMS for lab workflow management and proprietary algorithms for tumor/normal profiling and HLA typing.

Where is Personalis headquartered?

Personalis is headquartered in Fremont, California. It is a public company founded in 2011 with 201–500 employees.

How this profile is built

Personalis, Inc.'s technology stack, projects, and hiring signals are inferred from public hiring and company data — career pages, public listings, and company web presence — then clustered and de-duplicated. Figures are estimates that refresh over time. Read our full methodology →

This is not an official vendor or customer list. It is a technology-adoption signal inferred from public data, intended for B2B research.