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Company profile

Protagonist Therapeutics Tech Stack

Peptide drug discovery and development for oral NCE therapeutics

Biotechnology Newark, California 51–200 employees Founded 2006 Public Company

Protagonist Therapeutics discovers and develops peptide-based drug candidates engineered for oral stability. Its stack pairs lab and chemistry tools (ChemDraw, SciFinder, LC-MS/MS, LIMS) with pharmacometrics software (Phoenix WinNonlin, NONMEM) and GPT, Gemini and MCP. A Head of AI search signals AI moving into discovery. Senior and director-heavy hiring in research, plus a Toxicology Director role, points to pipeline molecules advancing from Phase 1 through Phase 3.

Tech Stack 23 technologies

Core StackSmartsheet Python AWS Zoom Intune MATLAB ChemDraw SciFinder Spotfire LIMS HPLC HPLC-MS GraphPad Prism LC-MS/MS Phoenix WinNonlin NinjaOne Freshservice NONMEM GPT Gemini Azure GCP MCP

What Protagonist Therapeutics Is BuildingChallenges and projects from their job posts

◆Challenges

Integrating preclinical, clinical, CMC and regulatory execution
Meeting accelerated development and trial timelines
Managing CRO, consultant and vendor risk
Maintaining GMP compliance
Improving study processes

▲Active Projects

Advancing Phase 1 to Phase 3 clinical trials
Nonclinical toxicology strategies for pipeline molecules
GMP API manufacturing and synthesis scale-up
Compound optimization to advance leads
Clinical site recruitment strategy
Analytical laboratory oversight

Hiring Activity

Decelerating15 roles · 3 in 30d

Department

Research

Engineering

Ops

Healthcare

Manufacturing

Pharmacology

Seniority

Senior

Director

Lead

Mid

Staff

Notable leadership hires: Toxicology Director, Head of AI

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About Protagonist Therapeutics

Protagonist Therapeutics is a publicly traded biopharmaceutical company (Nasdaq: PTGX) headquartered in Newark, California, founded in 2006. It runs a proprietary platform for designing peptide new chemical entities de novo, tuning potency and selectivity and applying chemical modifications for oral delivery. The company targets disease areas with significant unmet medical need. It employs 51–200 people and hires in the United States across research, engineering, operations, manufacturing and pharmacology.

HeadquartersNewark, California

Company Size51–200 employees

Founded2006

Hiring MarketsUnited States

Frequently Asked Questions

What tech stack does Protagonist Therapeutics use?

Scientific tools include ChemDraw, SciFinder, Spotfire, LIMS, HPLC-MS, GraphPad Prism, Phoenix WinNonlin and NONMEM, alongside Python, MATLAB, AWS, Azure, GCP, Smartsheet and IT tools like Intune and Freshservice.

Is Protagonist Therapeutics hiring for AI roles?

Yes. It is recruiting a Head of AI, and its stack already includes GPT, Gemini and MCP, suggesting AI is being formalized as a leadership function. Overall hiring velocity is decelerating.

Where is Protagonist Therapeutics headquartered?

Protagonist Therapeutics is headquartered in Newark, California, and its current hiring is focused in the United States.

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How this profile is built

Protagonist Therapeutics's technology stack, projects, and hiring signals are inferred from public hiring and company data — career pages, public listings, and company web presence — then clustered and de-duplicated. Figures are estimates that refresh over time. Read our full methodology →

This is not an official vendor or customer list. It is a technology-adoption signal inferred from public data, intended for B2B research.