Cloud-native computational molecular design software for drug discovery
OpenEye, now part of Cadence, builds molecular modeling toolkits and the Orion cloud design platform for pharma and biotech research. The stack pairs a C++ and Python scientific core with Go, Django and PostgreSQL on AWS, plus a WebGL and WebAssembly front end, pointing to compute-heavy 3D visualization delivered in the browser. Lean, lead-level engineering hiring centers on modernizing legacy code and expanding into biologics and AI-driven modeling.
OpenEye, Cadence Molecular Sciences develops software, toolkits and design services for computational molecular design across the drug discovery process. Its science centers on analyzing the shape and electrostatics of 3D molecular structures for pharmaceutical and biotechnology organizations. Its applications are unified in Orion, a cloud-native molecular design platform combining computation, storage, data sharing and visualization. Founded in 1997 and headquartered in Santa Fe, New Mexico, the company has 51–200 employees, offices in Boston, Cologne and Tokyo, and operates under Cadence Design Systems.
OpenEye uses C++, Python, Go, Django, PostgreSQL and Docker on AWS, with a TypeScript front end built on Vue, Nuxt, Next.js, WebGL and WebAssembly, plus TeamCity and CMake for builds.
OpenEye is headquartered in Santa Fe, New Mexico, with additional offices in Boston, Massachusetts; Cologne, Germany; and Tokyo, Japan.
Job posts point to a cloud-based biologics discovery platform, AI-driven molecular modeling, protein informatics expansion, new compute and storage architecture, and modernizing existing software.
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OpenEye, Cadence Molecular Sciences's technology stack, projects, and hiring signals are inferred from public hiring and company data — career pages, public listings, and company web presence — then clustered and de-duplicated. Figures are estimates that refresh over time. Read our full methodology →
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