Broad Institute of MIT and Harvard Tech Stack
Biomedical research institute advancing genomics, proteomics, and cancer therapeutics
Broad Institute operates a large-scale research organization spanning genomics, proteomics, chemical biology, and cancer therapeutics across three organizational structures: core labs, programs, and platforms. The tech stack reflects a hybrid research environment—AWS, GCP, Python, R, Jupyter for computational work; specialized instruments (10x Genomics, Illumina, LC-MS) for wet-lab operations; and enterprise systems (SAP, Jira, Confluence) for coordination. Current hiring is research-heavy (25 of 49 open roles), with mid-level scientists dominating the pipeline, while SAP migration (ECC → S/4HANA) and pain points around financial reporting standardization and lab IT integration suggest operational scaling challenges.
Tech Stack 34 technologies
What Broad Institute of MIT and Harvard Is Building
◆Challenges
- Employee relations challenges
- Compliance & risk management
- Converting genomic data to patient benefit
- Integrating lab equipment into it infrastructure
- Ensuring accuracy and timeliness of financial reporting
- Operational challenges
- Ensuring compliance with federal regulations
- Maintaining audit-ready documentation
- Standardizing financial tools
- Implementing process changes
▲Active Projects
- Cloud-based orchestration platform for genomics pipelines
- Ctdna shedding mechanism research
- Resistance development to newer antibody-drug conjugate therapies in breast cancer
- Mechanisms of resistance to small molecule inhibitors in gastrointestinal cancers
- New protocols & products
- Workflow changes
- Validation experiments
- Proteomic and peptidomic projects
- Sample preparation and data analysis pipelines
- Profiling molecular contents and biological states of thousands of individual cells in brain tissue
Hiring Activity
Department
Seniority
Notable leadership hires: Operations Director
