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Colossal Biosciences Tech Stack

CRISPR-based de-extinction and endangered species restoration

Biotechnology Research Dallas, TX 51–200 employees Privately Held

Colossal applies CRISPR and advanced reproductive biology to restore extinct and endangered species. The tech stack is heavily weighted toward bioinformatics (Benchling, SnapGene) and lab infrastructure, with no cloud data platforms or ML tooling visible—reflecting a bench-science operation rather than a software-first biotech. Active hiring skews research and healthcare, concentrated at senior and mid-level, with pain points centered on scaling embryo development protocols and veterinary infrastructure across non-model organisms.

Tech Stack 33 technologies

Core StackLinux Slack Zoom Okta Zscaler DocuSign Windows Server Active Directory Hyper-V Python Benchling SnapGene Windows macOS Google Workspace Microsoft 365 Dante BrightSign Adobe Zoom Rooms DNS DHCP Red Hat Enterprise Linux Ubuntu Debian Bash Proxmox Meraki Dashboard VLAN iSCSI+3 more

What Colossal Biosciences Is Building

◆Challenges

Developing protocols for non-model organisms
Maintaining stable embryo development rates
Building clinical systems from the ground up
Scaling veterinary programs
Expanding animal programs

▲Active Projects

Next-gen sequencing
Animal care
Bioengineering
Stem cell platform development for non-model species
Cellular engineering for marsupial species
In vitro production of embryos in mice, livestock, wildlife species
Production of embryos with edited genomes using advanced art
Derivation of embryonic stem cells from ivf, scnt, interspecies scnt embryos
Clinical sop development for preventative medicine
Anesthesia protocol design

Hiring Activity

Accelerating10 roles · 6 in 30d

Department

Research

4

Healthcare

2

Support

2

Animal

1

Ops

1

Seniority

Senior

5

Mid

3

Intern

1

Junior

1

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About Colossal Biosciences

Colossal is a genomics and genetic engineering company headquartered in Dallas, TX, focused on species de-extinction and ecosystem restoration using CRISPR technology. The company works across three operational areas: next-generation sequencing and analysis, stem cell and embryo engineering (particularly in marsupials and livestock), and veterinary clinical protocols for preventative medicine. The organization combines bench research, animal husbandry, and clinical development—evidenced by active work on embryo production, anesthesia protocol design, and scaling animal care programs. Current headcount sits in the 51–200 range with accelerating hiring velocity.

HeadquartersDallas, TX

Company Size51–200 employees

Hiring MarketsUnited States

Frequently Asked Questions

What is Colossal Biosciences working on?

Colossal focuses on next-gen sequencing, stem cell platform development for non-model species (particularly marsupials), in vitro embryo production with edited genomes, and clinical SOP development for preventative medicine.

What bioinformatics tools does Colossal use?

Benchling and SnapGene are the primary bioinformatics platforms in the stack, paired with Linux environments (Red Hat, Ubuntu, Debian) and Python for computational work.

Where is Colossal Biosciences headquartered?

Colossal is headquartered in Dallas, TX and currently hires across the United States, with active roles in research, healthcare, animal care, and operations.