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Company profile

Calico Life Sciences Tech Stack

Aging-biology R&D company building ML-driven peptide drug discovery

Biotechnology Research South San Francisco, CA 201–500 employees Founded 2013 Privately Held
calicolabs.com LinkedIn

Calico Life Sciences pairs wet-lab chemistry (HPLC, LC-MS, Benchling) with a serious ML compute stack (GCP, Kubernetes, Kueue, Ray, JAX, PyTorch, AlphaFold) and is now adopting Gemini. Job posts point to consolidating legacy compute into a centralized GCP landing zone and squeezing more from GPU/TPU capacity. Accelerating, director-heavy research hiring alongside regulatory and a Medical Director role suggests programs moving toward the clinic.

Tech Stack 36 technologies

Core StackTerraform Kubernetes Docker Python PyTorch NetSuite TensorFlow MATLAB BigQuery React Apache Spark FastAPI AWS HPLC Flash GCP Kueue Ray LC-MS Phoenix WinNonlin JAX Agilent Coupa qPCR PyMOL Benchling TIFF Zarr Transformers AlphaFold+1 more
AdoptingGemini

What Calico Life Sciences Is BuildingChallenges and projects from their job posts

◆Challenges

  • Consolidating legacy compute environments onto centralized GCP
  • Optimizing GPU/TPU utilization
  • Safe, scalable synthetic processes
  • Managing CRO relationships
  • Timely delivery of DMPK data
  • Streamlining internal approval workflows

▲Active Projects

  • Next-generation ML platform
  • Centralized GCP landing zone with GPU/TPU optimization
  • Peptide drug discovery and therapeutic peptide optimization
  • High-throughput automated peptide synthesis
  • Bridging computation and chemistry
  • Technology transfer to contract manufacturing organizations

Hiring Activity

Accelerating20 roles · 6 in 30d

Department

Research
10
Engineering
3
Regulatory
2
Business
1
Finance
1
Healthcare
1
Marketing
1

Seniority

Director
6
Senior
6
Junior
3
Principal
3
Lead
1

Notable leadership hires: Medical Director

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About Calico Life Sciences

Calico Life Sciences is a privately held research and development company founded in 2013 and headquartered in South San Francisco, CA. It studies the biology of human aging and works to develop therapeutics for age-related diseases, partnering with academic and industry groups. The company employs 201–500 people and hires in the United States. Its work spans peptide drug discovery, synthetic chemistry, DMPK and computational research supported by cloud and ML infrastructure.

HeadquartersSouth San Francisco, CA
Company Size201–500 employees
Founded2013
Hiring MarketsUnited States

Frequently Asked Questions

What tech stack does Calico Life Sciences use?

Calico runs on GCP with Terraform, Kubernetes, Docker, Kueue and Ray, uses Python, JAX, PyTorch, TensorFlow and AlphaFold for ML, Benchling for lab data, and NetSuite and Coupa for finance and procurement.

What is Calico Life Sciences working on?

Current projects include a next-generation ML platform, a centralized GCP landing zone, GPU/TPU capacity optimization, peptide drug discovery campaigns and automated high-throughput peptide synthesis.

Is Calico Life Sciences hiring?

Yes, hiring is accelerating in the United States, led by research with director and senior-level roles, plus engineering, regulatory and a Medical Director position.

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How this profile is built

Calico Life Sciences's technology stack, projects, and hiring signals are inferred from public hiring and company data — career pages, public listings, and company web presence — then clustered and de-duplicated. Figures are estimates that refresh over time. Read our full methodology →

This is not an official vendor or customer list. It is a technology-adoption signal inferred from public data, intended for B2B research.