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BillionToOne Tech Stack

Molecular diagnostics platform for prenatal and liquid biopsy screening

Biotechnology Research Menlo Park, California 501–1,000 employees Founded 2016 Privately Held

BillionToOne operates a molecular counting platform for precision diagnostics, with heavy commercial focus: 115 of 169 open roles are sales-driven, concentrated on ObGyn clinics and prenatal screening adoption. Stack mirrors a clinical-software hybrid — Epic, Cerner, Athena (EHR integration), Python/Django/PostgreSQL backend, React frontend — suggesting deep healthcare workflow integration rather than consumer-facing polish. Active hiring velocity across sales and engineering signals execution against market-development roadmaps for fetal risk screens and liquid biopsy products.

Tech Stack 36 technologies

Core StackEpic Systems Python Django PostgreSQL React TypeScript AWS Heroku Salesforce Cursor GitHub Copilot Linux GitHub Docker Flask OpenAI NetSuite Unity Google Docs Word Excel Cerner Athena HL7 FHIR Claude LIMS AWS CDK Alpine.js HTMX+6 more

What BillionToOne Is Building

◆Challenges

Increasing utilization of unity fetal risk screen
Portable emr transfer
Increasing revenue
Digitizing paper-based workflows
Driving market development
Increasing utilization of prenatal screening
Expanding market share in obgyn clinics
Identifying commercial opportunities for growth
High-throughput clinical patient testing
Scaling reporting needs

▲Active Projects

Increasing utilization of unity fetal risk screen
Driving market development
Northstar liquid biopsy sales
Launch single-gene nipt screen in la north
Seamless digital experience for clinicians and patients
Data-driven sales strategy
Strategic business plan to grow utilization
Direct sales to obgyns, mfms, and genetic counselors
Market development in obgyn clinics
Market development strategy

Hiring Activity

Accelerating170 roles · 75 in 30d

Department

Sales

115

Engineering

19

Healthcare

11

Research

5

Data

4

Support

4

Ops

3

Product

3

Seniority

Mid

107

Senior

29

Junior

13

Manager

12

Lead

4

Director

2

Intern

2

Notable leadership hires: Market Access Director

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About BillionToOne

BillionToOne is a precision diagnostics company developing a proprietary molecular counting platform that quantifies DNA at single-molecule resolution to improve accuracy in disease detection. The product portfolio centers on prenatal screening (fetal risk assessment, single-gene NIPT) and liquid biopsy applications. The company sells directly to ObGyns, maternal-fetal-medicine specialists, and genetic counselors in the United States, Canada, and Peru. With 501–1,000 employees headquartered in Menlo Park, the organization balances clinical validation with commercial distribution, as evidenced by substantial sales hiring and active projects around utilization expansion and market penetration in ObGyn networks.

HeadquartersMenlo Park, California

Company Size501–1,000 employees

Founded2016

Hiring MarketsUnited States, Canada, Peru

Frequently Asked Questions

What tech stack does BillionToOne use?

BillionToOne integrates EHR platforms (Epic, Cerner, Athena) with Python/Django/PostgreSQL backend, React/TypeScript frontend, AWS infrastructure, and clinical-lab standards (HL7, FHIR, LIMS). Also using GitHub Copilot and Claude for development acceleration.

What products is BillionToOne launching?

Active projects include Unity fetal risk screen (utilization expansion), single-gene NIPT screen launch in LA North, and northstar liquid biopsy sales. Focus is on increasing adoption among ObGyns and maternal-fetal-medicine specialists.