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Twist Bioscience Tech Stack

Silicon-based synthetic DNA manufacturing for life sciences research

Biotechnology Research South San Francisco, California 501–1,000 employees Founded 2013 Public Company

Twist Bioscience manufactures synthetic DNA using a proprietary silicon-based process, serving researchers in medicine, agriculture, and industrial chemicals. The company is mid-scale (501–1,000 employees) with a sales-led hiring profile (26 active sales roles vs. 13 engineering) and decelerating hiring velocity. Current focus spans NGS workflow optimization, antibody discovery projects, and ERP/CPQ system enhancements—alongside pain points around revenue forecasting and production scheduling—indicating tension between scaling manufacturing capacity and sales velocity.

Tech Stack 78 technologies

Core StackSalesforce Django Workato Jira MuleSoft Apex Greenhouse SalesLoft ADP Workday AWS Docker Python Kubernetes Dell Boomi MES Excel Word Salesforce Sales Cloud Salesforce Data Cloud Salesforce Marketing Cloud Tableau CRM Microsoft Office Google Workspace Qubit TapeStation LIMS Nextflow AWS EKS AWS Batch+48 more

AdoptingSalesforce Marketing Cloud

What Twist Bioscience Is Building

◆Challenges

Minimizing time to revenue
Identifying unmet customer needs
Accurate revenue forecasting
Improving hiring efficiency
Automation integration into lab workflows
Efficiency and process improvement
Maintaining production schedule
Maintaining data integrity in sap
Maximizing revenue
Risk mitigation planning

▲Active Projects

Ngs workflow optimization
Supply agreement development
Antibody discovery projects
Erp and cpq system enhancements
Integration of new qc technologies
Improving technical services and capabilities
Internal projects to improve efficiency and processes
Enterprise systems integration projects
Antibody optimization
Uat for new company initiatives

Hiring Activity

Decelerating100 roles · 25 in 30d

Department

Sales

26

Research

15

Engineering

13

Ops

11

Finance

7

Support

7

Marketing

6

Manufacturing

4

Seniority

Senior

43

Mid

34

Junior

6

Staff

5

Director

4

Manager

3

Lead

1

VP

1

Notable leadership hires: CRM Director

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About Twist Bioscience

Twist Bioscience is a publicly traded synthetic biology company that designs and manufactures synthetic DNA for life science research and development. The platform includes gene synthesis, oligonucleotide pools, biopharma services, and NGS target enrichment tools. Researchers use the product across drug discovery, gene therapy, and industrial biotech workflows. The company operates manufacturing facilities and technical services from South San Francisco, with hiring footprint across the United States, Sweden, Uganda, Singapore, and the United Kingdom. Salesforce (Sales Cloud, Data Cloud, Marketing Cloud) and AWS form the core commercial and cloud infrastructure; LIMS, Nextflow, and MES systems manage lab workflows and production.

HeadquartersSouth San Francisco, California

Company Size501–1,000 employees

Founded2013

Hiring MarketsUnited States, Sweden, Uganda, Singapore, United Kingdom

Frequently Asked Questions

What technology does Twist Bioscience use for DNA synthesis?

Twist uses a proprietary silicon-based manufacturing process. The platform sits on Salesforce, AWS, Docker, Kubernetes, Python, Nextflow, and specialized lab systems (LIMS, MES, TapeStation, Qubit) for quality control and sequencing workflows.