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Madrigal Pharmaceuticals Tech Stack

Clinical-stage biotech developing MASH therapeutics with AI-driven operations

Pharmaceutical Manufacturing Conshohocken, Pennsylvania 501–1,000 employees Founded 2016 Public Company

Madrigal is a public biopharmaceutical company developing treatments for metabolic dysfunction-associated steatohepatitis (MASH), a progressive liver disease. The tech stack reveals a company mid-build on AI and data infrastructure—adopting AutoGen, CrewAI, and Langfuse alongside traditional pharma tools (Veeva RIM, dbt, Databricks)—while hiring heavily in healthcare, research, and sales roles at director and senior levels. Active projects span clinical trial execution, regulatory submissions, and real-world evidence generation, aligned with multiple pain points around document efficiency, compliance (SOX 404, TMF archival), and trial scaling.

Tech Stack 27 technologies

Core StackDatabricks SageMaker Vertex AI n8n Workday Alation dbt Power BI NetSuite AutoGen CrewAI Azure AI Search Dify AgentOps Langfuse Word ADP Workforce Now GPT-4 Microsoft Fabric Synapse Coupa Azure Azure Entra ID Microsoft Office Concur OneLake Veeva RIM

What Madrigal Pharmaceuticals Is Building

Challenges

  • Ensuring right talent
  • Ensuring compliance with sox 404
  • Optimal pricing and reimbursement
  • Optimizing document development efficiency
  • Improving patient access and adherence
  • Mitigate supply chain disruptions
  • Ensuring tmf health and archival
  • Compliance issues
  • Expanding clinical trial operations
  • Strengthening workforce strategy

Active Projects

  • Analytics
  • Clinical trial documentation for phase 1-4
  • Global clinical trial execution
  • Regulatory strategy for nda/bla submissions
  • Global integrated evidence plans
  • Business development and m&a projects
  • Real-world evidence generation
  • Marketing initiatives targeting endocrinologists
  • Standard reporting for ongoing compliance check
  • Medical information resource document development

Hiring Activity

Accelerating100 roles · 45 in 30d

Department

Healthcare
20
Research
12
Sales
12
Ops
8
Data
7
Marketing
6
Finance
5
HR
5

Seniority

Director
48
Senior
30
Mid
8
Manager
7
Lead
3
VP
2
Principal
1

Notable leadership hires: Health Systems Director, Scientific Director, Medical Director, HR Communications Director, Key Account Director

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About Madrigal Pharmaceuticals

Madrigal Pharmaceuticals focuses on developing novel therapeutics to halt or reverse liver fibrosis in MASH patients before progression to cirrhosis, liver failure, or cancer. Founded in 2016 and now public, the company operates across 501–1,000 employees based in Conshohocken, Pennsylvania, with hiring in the United States, Switzerland, and Peru. The operational footprint spans clinical development (phase 1–4 trials), regulatory strategy for FDA/BLA submissions, business development, and market access. Core pain points center on workforce alignment, document development efficiency, trial expansion, and supply-chain resilience in a highly regulated environment.

HeadquartersConshohocken, Pennsylvania
Company Size501–1,000 employees
Founded2016
Hiring MarketsUnited States, Switzerland, Peru

Frequently Asked Questions

What is Madrigal Pharmaceuticals working on?

Madrigal develops therapeutics for MASH, a metabolic liver disease. Active work includes phase 1–4 clinical trials, regulatory filings, real-world evidence studies, and marketing to endocrinologists.

What tech stack does Madrigal Pharmaceuticals use?

Madrigal runs on AutoGen, CrewAI, Databricks, Azure AI, SageMaker, Vertex AI, Veeva RIM (regulatory), dbt, Power BI, Workday, Coupa, NetSuite, and Microsoft cloud services including Fabric and Synapse.

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