City of Hope Tech Stack

Comprehensive cancer center with integrated research, clinical care, and translational medicine

Hospitals and Health Care Duarte, CA 10,001+ employees Nonprofit

City of Hope is a National Cancer Institute-designated comprehensive cancer center operating a multi-state clinical network alongside active research programs in oncology, diabetes, and translational genomics. The tech stack reflects dual operational modes: clinical systems (Epic, RIS, Allscripts) supporting 489 healthcare staff, and research-grade analytics tools (Python, R, TensorFlow, PyTorch, pandas, scikit-learn, LangChain, CyTOF, LC-MS/MS) backing 114 research roles. Active hiring across healthcare, research, and ops suggests scaling both patient capacity and translational research output, while pain points around medication costs, patient experience, and workforce optimization point to operational friction common at large academic medical centers.

Tech Stack 56 technologies

Core StackPython Epic Systems C++ Siemens ADP AWS pandas scikit-learn TensorFlow PyTorch LangChain R Word PowerPoint Excel Radiology Information System Allscripts BMS Microsoft Office CyTOF REDCap OnBase PeopleSoft ServSafe LC-MS/MS ICP-MS Agilent QuickBooks Online Windows Azure+26 more

What City of Hope Is Building

◆Challenges

Reducing medication costs
Compliance with regulations
Improving patient experience
Workforce optimization
Improving patient safety
Expanding cutting-edge division
Performance improvement analysis
Expanding surgical oncology program
Maintaining cgmp compliance
Acute symptom management

▲Active Projects

Clinical trials
Surgical oncology program development
Genetic and epigenetic basis of gi cancers
New clinical programs
Single-cell multi-omic biomarker discovery
Translational and clinical research in breast cancers
Irb review process
Patient education programs specific to cancer care
Evaluation and treatment center (etc)
Multiple myeloma and lymphoma research

Hiring Activity

Steady700 roles · 290 in 30d

Department

Healthcare

489

Research

114

Ops

Finance

Engineering

Support

Security

Operations

Seniority

Mid

261

Senior

195

Junior

191

Manager

Director

Staff

Lead

Intern

Notable leadership hires: Head and Neck Medical Oncologist, Medical Director, Medical Director of Gastroenterology, Chief of Hematology, Director of Nursing

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About City of Hope

City of Hope is a nonprofit cancer research and treatment organization founded in 1913, now operating as one of the largest integrated cancer centers in the U.S. The organization combines clinical care delivery across Southern California (with expansion into Orange County, Atlanta, Chicago, and Phoenix), NCI-designated research programs, medical education, and commercial innovation initiatives. Core strengths include oncology spanning brain, breast, gastrointestinal, gynecologic, liver, lung, and hematologic malignancies, alongside endocrinology and translational genomics research. With 10,000+ employees and active projects in surgical oncology expansion, biomarker discovery, and clinical trial execution, City of Hope operates at the intersection of patient care and research translation—its research discoveries have yielded multiple cancer medicines, synthetic insulin, and monoclonal antibody platforms.

HeadquartersDuarte, CA

Company Size10,001+ employees

Hiring MarketsUnited States

Frequently Asked Questions

What is City of Hope's technology stack?

Clinical operations run on Epic Systems, Allscripts, and Radiology Information Systems. Research uses Python, R, C++, TensorFlow, PyTorch, pandas, scikit-learn, and LangChain for analytics and ML. Lab infrastructure includes CyTOF, LC-MS/MS, ICP-MS, and Agilent for multi-omic analysis. Enterprise tools: AWS, Azure, PeopleSoft, OnBase, ADP.

What research is City of Hope working on?

Active projects include clinical trials, surgical oncology program expansion, single-cell multi-omic biomarker discovery, translational and clinical research in breast cancers, multiple myeloma and lymphoma research, and genetic/epigenetic studies of GI cancers.