RBQM platform for clinical trial risk management and monitoring
TRI operates OPRA, a Risk-Based Quality Management platform deployed across 450+ clinical trials. The tech stack—C#, Azure DevOps, PostgreSQL, MongoDB, Docker, Kubernetes—reflects a mature, containerized SaaS built for regulated environments. Hiring is accelerating across engineering and sales with a balanced mid/senior mix, while active projects (platform development, pipeline strengthening, account profiling) suggest TRI is scaling both product and go-to-market.
TRI develops OPRA, a Risk-Based Quality Management (RBQM) platform for clinical trial teams. The product covers risk assessment, risk management, and central monitoring through two core modules—OPRA-RAM and OPRA-CM—and is built by operational experts with real-world trial experience. Deployed on over 450 clinical trials globally, OPRA supports compliance with ICH E6, E8, and Good Clinical Practice standards. The company operates from Cambridge and serves mid-to-large pharmaceutical, biotech, and CRO customers navigating regulatory complexity and patient safety requirements.
TRI builds OPRA on C#, Azure DevOps, PostgreSQL, MongoDB, Docker, and Kubernetes, with REST APIs and Swagger for integration. Frontend uses JavaScript and TypeScript. Salesforce handles CRM; Jira and Confluence manage development workflows.
OPRA is deployed on over 450 clinical trials globally, making it one of the most widely adopted RBQM platforms in the sector.
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