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Tempus AI Tech Stack

AI-powered precision medicine platform for clinical decision support

Biotechnology Research Chicago, IL 1,001–5,000 employees Founded 2015 Public Company

Tempus applies machine learning to clinical and molecular data to guide physician decision-making in real time. The stack is heavy on ML infrastructure—PyTorch, TensorFlow, Transformers, Horovod, Ray Data—paired with clinical tools (LIMS, Illumina sequencers) and EHR integration (currently adopting). Active pain points around adoption velocity (online ordering, MRD testing, diagnostic portfolio uptake) and regulatory complexity suggest the company is navigating the friction between AI innovation and clinical workflow embedding, a challenge reflected in their sales-led hiring mix (84 sales roles vs. 22 engineering).

Tech Stack 81 technologies

Core StackPyTorch TensorFlow Python Apache Airflow Kubernetes Salesforce Workday TypeScript FastAPI Node.js NestJS React React Native PostgreSQL Jest LangChain Transformers Horovod Ray Data Hugging Face Datasets Kubeflow Pipelines GCP Azure Excel PowerPoint Microsoft Office LIMS Illumina NovaSeq 6000 Pytest LangGraph+45 more

AdoptingEHR

ReplacingMicrosoft Exchange AWS Outlook SharePoint OneDrive

What Tempus AI Is Building

◆Challenges

Low adoption of online ordering
Driving adoption of mrd testing
Reducing turnaround time
Adopting mrd testing
Scope creep
Driving adoption of diagnostic portfolio
Payer reimbursement challenges
Embedding into clinical pathways
Improving workflow efficiencies
Complex regulated diagnostic product development

▲Active Projects

Compliance with web-based molecular tools
Online ordering adoption via tempus hub
Implement laboratory services agreements
Develop comprehensive business plan for territory
Ai & llm integration into workflows
Translational research projects for early stage biopharmaceutical partners
Territory business plan development
Rwe studies
Precision medicine initiatives in va
Liquid biopsy (xf) portfolio development

Hiring Activity

Steady260 roles · 110 in 30d

Department

Sales

84

Research

46

Data

26

Healthcare

24

Engineering

22

Product

17

Ops

9

HR

5

Seniority

Senior

80

Mid

63

Director

41

Manager

29

Junior

22

Staff

10

VP

6

Intern

2

Notable leadership hires: Medical Director, Product Director, Enterprise Solutions Director, Head of Communications, Medical Affairs Director

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About Tempus AI

Tempus AI is a public biotech-tech company applying artificial intelligence to advance precision medicine. The platform ingests clinical and molecular data to generate insights that support real-time, personalized treatment decisions for physicians and patients. Core projects include AI/LLM integration into clinical workflows, real-world evidence studies, liquid biopsy portfolio development, and expansion of laboratory services partnerships. The company operates at scale across the US, Spain, and UK, with balanced investment in sales, research, and data science teams. Regulatory compliance, diagnostic adoption, and clinical workflow integration remain central operational challenges.

HeadquartersChicago, IL

Company Size1,001–5,000 employees

Founded2015

Hiring MarketsUnited States, Spain, United Kingdom

Frequently Asked Questions

What machine learning frameworks does Tempus AI use?

Tempus runs PyTorch, TensorFlow, and Transformers as core ML frameworks, supported by Horovod for distributed training, Ray Data for data processing, and Hugging Face Datasets. LangChain and LangGraph indicate recent LLM integration work.