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Mayo Clinic Tech Stack

Academic medical center integrating clinical care, research, and AI-driven surgery programs

Hospitals and Health Care Rochester, Minnesota 10,001+ employees Nonprofit

Mayo Clinic operates as a large integrated healthcare delivery and research organization running 1,535 active roles, with healthcare and nursing staff comprising 85% of headcount. The tech stack reveals a dual operation: Epic dominates clinical workflows, while Python, TensorFlow, PyTorch, and AWS tooling support an active research and AI engineering division. Active projects around AI deployment in surgery and genomics research, paired with pain points in staffing and accreditation burden, indicate a system scaling both volume and complexity.

Tech Stack 86 technologies

Core StackPython MATLAB C++ Epic Systems TensorFlow PyTorch Linux MySQL Redis Docker Revit Epic qPCR AWS EMR PACS Windows Internet Explorer Watchman Impella CMMS Word Excel PowerPoint GCP R Microsoft Office ATAC-seq RNA-seq Autodesk Construction Cloud Micros+56 more

What Mayo Clinic Is Building

◆Challenges

High seasonal work volume
Developing new business opportunities
Complex technical issues
High volume requests
Staffing shortage
Contract negotiation
Reducing healthcare costs
Patient flow management
Reducing burden of accreditation processes
Launching new laboratory it infrastructure

▲Active Projects

Clinical trials
Nurse residency program
Bold.forward.unbound
Develop mnt practice guidelines and protocols
Protocol development and maintenance
Multidisciplinary voice clinic
Clinical genomics research portfolio
Power plant expansion
Deploying ai approaches within surgery
Cancer initiation research

Hiring Activity

Steady1,500 roles · 650 in 30d

Department

Healthcare

772

Nursing

360

Research

97

Ops

68

Engineering

41

Sales

24

Security

18

Support

18

Seniority

Junior

581

Mid

566

Senior

265

Intern

31

Lead

31

Manager

29

Director

18

Principal

6

Notable leadership hires: Unit Head, Lab Director, Development Assistant Director, Accreditation Director, Finance Compliance Director

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About Mayo Clinic

Mayo Clinic is a nonprofit, integrated medical group practice headquartered in Rochester, Minnesota, operating as the largest not-for-profit medical group in the world. The organization provides clinical care across specialties including cardiology, oncology, transplantation, and neurosciences, while running parallel research portfolios in clinical genomics and emerging AI applications. The operational footprint spans clinical trials, residency training programs, protocol development, and laboratory infrastructure expansion, serving patient populations at scale with reported recognition for quality outcomes.

HeadquartersRochester, Minnesota

Company Size10,001+ employees

Hiring MarketsUnited States

Frequently Asked Questions

What technologies does Mayo Clinic use in clinical operations?

Epic Systems is the primary clinical platform. Supporting infrastructure includes PACS (medical imaging), Windows, Microsoft Office, and Internet Explorer for legacy workflows, alongside AWS EMR and MySQL for data processing and storage.

What AI and research tools does Mayo Clinic use?

The stack includes Python, TensorFlow, PyTorch, R, and MATLAB for research computing. Genomics work leverages RNA-seq and ATAC-seq. GCP and AWS EMR support cloud-based analytics and machine learning workloads.