Genentech Tech Stack

Drug discovery and manufacturing biotech with AI-driven development pipelines

Biotechnology Research South San Francisco, California 10,001+ employees Founded 1976 Privately Held

Genentech operates a large-scale biotech R&D and manufacturing organization across oncology, immunology, neuroscience, and other therapeutic areas. The tech stack reveals a dual-mode operation: scientific computing (Python, Java, C++, Go, Rust, SageMaker) for drug discovery and clinical analytics, paired with industrial control and ERP infrastructure (SAP S/4HANA, DeltaV SCADA, PLCs, HMI) for regulated manufacturing. Active hiring in research, data, and engineering—with a senior-skewed profile—combined with projects around AI for drug discovery, clinical development platforms, and manufacturing execution systems (MES) suggests a push to automate both discovery cycles and compliance-heavy production workflows.

Tech Stack 120 technologies

Core StackPython Java AWS Terraform Helm Kubernetes AWS RDS SageMaker C++ Go Rust Workday SAP Active Directory SAP S/4HANA Git Bash AWS EKS DeltaV PLC SAP HANA Excel Veeva Emerson DeltaV AVEVA PI SCADA DCS PLCs HMI CRM+86 more

AdoptingSAP ERP MCP

What Genentech Is Building

◆Challenges

Seamless data sharing across teams
Modernizing computational data ecosystems
Improving maintenance automation
Complex accounts across ecosystems
Ensuring compliance with evolving regulatory requirements
Eliminating silos
Increasing system uptime
Optimizing existing processes
Modernizing data acquisition and integration
Optimizing reliability maintainability availability

▲Active Projects

Ai for drug discovery
Clinical development plan implementation
Rcm implementation for gmp and non-gmp equipment
Facility startup and qualification
Early clinical development projects
Next-generation therapeutic molecule registration (tmr) platform
Mes recipe authoring for make/assess/release
Analytics/data strategy development
Lysosomal and mitochondrial quality control in neurodegenerative diseases
Data pipelines and applications for scientific data

Hiring Activity

Steady390 roles · 130 in 30d

Department

Research

Data

Engineering

Manufacturing

Healthcare

Ops

Marketing

Product

Seniority

Senior

158

Intern

Principal

Director

Lead

Mid

Manager

Junior

Notable leadership hires: Medical Director, Engagement Lead, Medical Population Science Lead, Project Director, Insights Enablement Lead

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About Genentech

Genentech is a pharmaceutical research and development company specializing in discovering and manufacturing therapeutic medicines for difficult-to-treat conditions. The company serves patients and healthcare providers globally across six therapeutic focus areas: oncology, immunology, tissue repair, neuroscience, infectious disease, metabolism, and ophthalmology. Operations span drug discovery (AI-enabled candidate screening), clinical development (regulatory submission and trial management), and regulated manufacturing (GMP and non-GMP facilities). The organization is scaled to support long-cycle R&D and multi-site production, with active efforts to modernize data pipelines, reduce operational silos, and improve system reliability across scientific and manufacturing environments.

HeadquartersSouth San Francisco, California

Company Size10,001+ employees

Founded1976

Hiring MarketsUnited States, United Kingdom, Germany, Switzerland

Frequently Asked Questions

What tech stack does Genentech use?

Scientific stack: Python, Java, C++, Go, Rust, AWS, SageMaker. Manufacturing/ERP: SAP S/4HANA, DeltaV SCADA, Veeva, Workday. Infrastructure: Kubernetes, Terraform, Git, AWS RDS/EKS.

What is Genentech working on?

AI for drug discovery, clinical development platforms (regulatory/TMR), manufacturing execution systems (MES) for GMP compliance, data pipeline modernization, and quality control research in neurodegenerative disease pathways.