Clinical-stage oncology company developing PRC2 and EGFR inhibitors
ORIC is a clinical-stage biopharmaceutical company with two lead candidates in prostate and lung cancer indications. The hiring mix is heavily regulatory and quality-focused—VP and director roles in regulatory affairs, CMC, and quality dominate the recent openings—indicating a company preparing for regulatory submissions and eventual commercialization. Tech stack reflects typical pharma infrastructure (Veeva Vault for document/regulatory management, NetSuite for financial operations, SAS for data analysis), with active adoption of Veeva Vault signaling investment in compliance-ready systems.
Notable leadership hires: Regulatory Affairs VP, CMC Regulatory Affairs Director, Director Quality
ORIC Pharmaceuticals develops small-molecule cancer therapies targeting resistance mechanisms. The company is advancing two clinical programs: ORIC-944, a PRC2 inhibitor for prostate cancer, and enozertinib, an EGFR/HER2 exon 20 inhibitor for non-small-cell lung cancer. Founded in 2014 and publicly traded, ORIC operates from dual hubs in South San Francisco and San Diego, California, with a workforce of 51–200 employees. The company's project and pain-point landscape centers on regulatory pathway efficiency, manufacturing scale-up, global compliance (21 CFR Part 11, GDPR), and launch readiness—typical challenges for a clinical program approaching IND or commercial submission phases.
ORIC has two clinical-stage candidates: ORIC-944, a PRC2 inhibitor for prostate cancer via the EED subunit, and enozertinib (ORIC-114), a brain-penetrant EGFR/HER2 exon 20 inhibitor for NSCLC.
ORIC uses Veeva Vault for regulatory and document management, NetSuite for financials, Coupa for procurement, SAS and LC-MS/HPLC for research, and GCP for cloud infrastructure. The company is actively adopting Veeva Vault.
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