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Obsidian Therapeutics Tech Stack

Engineered cell and gene therapies with controllable protein expression

Biotechnology Research Cambridge, MA 51–200 employees Founded 2015 Privately Held

Obsidian is a clinical-stage biotech focused on controllable cell and gene therapies, with their lead program (cytoTIL15) targeting TIL-based oncology. The hiring and project mix reveals a company in regulatory and manufacturing scale-up: directors and managers dominate across ops, quality, and clinical; active projects span GCP compliance, cGMP systems, TIL manufacturing optimization, and CDMO governance. Their tech stack (Benchling, qPCR, ddPCR) and adopting ITIL suggests engineering rigor around lab operations and process control.

Tech Stack 11 technologies

Core StackFortinet ADP Greenhouse NetSuite Cisco Meraki Benchling Egnyte FloQast qPCR ddPCR

AdoptingITIL

What Obsidian Therapeutics Is Building

◆Challenges

Compliance with ich-gcp
Ensuring cgmp compliance
Patient recruitment
Study timelines
Optimizing til manufacturing process
Regulatory audit readiness
Risk management & business continuity
It risk mitigation
Complex autologous cell therapy manufacturing network
Managing cdmo partnerships

▲Active Projects

Obx-115
Early phase cell therapy oncology clinical trials
Til manufacturing process optimization
Gcp clinical quality assurance program
Risk-based gcp quality management system
Audit program
Digital solutions & technology operations strategy
Business continuity and disaster recovery plans
Regulatory audit readiness
Cdmo governance system

Hiring Activity

Accelerating10 roles · 5 in 30d

Department

Ops

4

Quality

3

Clinical

1

Legal

1

Manufacturing

1

Research

1

Seniority

Director

4

Mid

3

Manager

2

Senior

2

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About Obsidian Therapeutics

Obsidian Therapeutics develops engineered cell and gene therapies designed to control protein expression for improved therapeutic outcomes in oncology and other intractable diseases. The company is headquartered in Cambridge, MA with laboratory operations in Bedford. They employ 51–200 people and are privately held with backing from institutional investors. Their clinical pipeline includes early-phase oncology trials, with manufacturing and quality operations central to their operational focus.

HeadquartersCambridge, MA

Company Size51–200 employees

Founded2015

Hiring MarketsUnited States

Frequently Asked Questions

What is Obsidian Therapeutics' lead program?

cytoTIL15, an engineered TIL therapy designed to enhance efficacy for more patients in oncology, using Obsidian's cytoDrive technology platform.

What tech does Obsidian Therapeutics use?

Benchling for research workflows, qPCR and ddPCR for molecular analysis, plus Cisco Meraki, Fortinet, Egnyte, ADP, Greenhouse, and NetSuite for ops and HR infrastructure.