Long-read DNA mapping platform for structural variant detection
Nabsys develops a nanodetector-based genome mapping platform (OhmX) designed to identify structural variants down to 300 bp—a capability gap between optical imaging and next-generation sequencing. The stack reveals a hardware-software hybrid: Python and C++ drive analysis pipelines (Flask, SQL, Kubernetes), while the core IP is solid-state nanodetection hardware. Active projects span chip design iteration with semiconductor partners, cancer-focused assay development, and algorithm validation against competing technologies, signaling a product still in clinical/commercial validation rather than mature deployment.
Nabsys is a biotechnology company focused on structural variant detection in genomics. The OhmX platform uses solid-state nanodetectors to read long DNA molecules and map chromosomal rearrangements, balanced and unbalanced, at high resolution without fluorescent labels. The company targets research institutions and clinical labs seeking cost-effective, rapid whole-genome structural variant analysis. At 11–50 employees with a 30-person engineering-to-manufacturing ratio, Nabsys operates as a hardware-software vendor in a space dominated by optical and sequencing incumbents. Current initiatives center on expanding application scope (cancer, rare disease), strengthening IT and data security infrastructure, and validating detection algorithms across external benchmarks.
Nabsys develops electronic genome mapping (EGM) using solid-state nanodetectors to detect structural variants as small as 300 bp across the whole genome without fluorescent imaging, offered through the OhmX platform.
Nabsys uses Python, C++, Flask, SQL, Kubernetes, and Docker for the analytics and infrastructure layer; TypeScript, Angular, and jQuery for frontend; and integrates with Illumina and PacBio sequencing platforms.
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