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Kriya Therapeutics, Inc. Tech Stack

Gene therapy developer advancing AAV programs in ophthalmology, metabolic disease, and neurology

Biotechnology Research Morrisville, NC 51–200 employees Founded 2019 Privately Held

Kriya is a clinical-stage gene therapy company with operations spanning Research Triangle Park and Palo Alto, structured around late-phase program analytics, manufacturing automation, and GMP compliance. The stack reveals a manufacturing-and-data operations company: NONMEM and ddPCR for assay work, SCADA/MES/DeltaV/Allen-Bradley for facility automation, and emerging adoption of MES with data analytics integration. Leadership hiring (directors, clinical data management lead) combined with heavy ops and quality focus signals scaling of GMP manufacturing and clinical operations for late-stage pipeline advancement.

Tech Stack 29 technologies

Core StackAllen-Bradley Siemens Python Expensify NONMEM R OSIsoft PI DeltaV Emerson DeltaV Tulip Ethernet/IP Modbus OPC BACnet PLC HMI SCADA MES HPLC Excel PowerPoint ddPCR CDISC Streamlit Shiny Microsoft Office Outlook Box SharePoint

AdoptingMES

What Kriya Therapeutics, Inc. Is Building

◆Challenges

Ensuring gxp compliance
Product quality
Late-phase analytical method development
Data integrity
Enhancing facility reliability
Maximizing uptime
Maintaining gmp-critical automation platforms
Aav vector release characterization
Improving reliability of gmp-critical automation
Continuous improvement of automation platforms

▲Active Projects

Late-phase program analytical method development
Capital project execution
Integration with mes and data analytics platforms
Lims implementation
Aav gene therapy vector release and characterization
Irt system development for clinical trials
Qualify and validate release testing methods
Configure osisoft pi data historian infrastructure
Support siemens desigo cc building management system operations
Support validation activities for automation systems

Hiring Activity

Accelerating40 roles · 25 in 30d

Department

Ops

7

Research

7

Quality

6

Engineering

3

Executive

3

Clinical

2

Data

2

Facilities

2

Seniority

Senior

11

Director

10

Mid

7

Junior

4

Manager

4

Intern

1

Notable leadership hires: Clinical Data Management Lead

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About Kriya Therapeutics, Inc.

Kriya Therapeutics develops gene therapies targeting ophthalmology, metabolic disease, and neurology, with a pipeline funded by over $900 million in capital. The company operates dual hubs in Morrisville, NC and Palo Alto, CA, structured around translational research, manufacturing, quality assurance, and clinical development. Active projects center on analytical method validation, AAV vector characterization, clinical trial infrastructure (IRT systems), and automation platform modernization (LIMS, OSIsoft PI, MES integration). The hiring acceleration across ops, research, and quality roles reflects manufacturing scale-up ahead of phase 3 and commercial readiness.

HeadquartersMorrisville, NC

Company Size51–200 employees

Founded2019

Hiring MarketsUnited States

Frequently Asked Questions

What is Kriya Therapeutics working on right now?

Late-phase analytical method development for AAV programs, LIMS implementation, MES integration with data analytics, IRT system configuration for clinical trials, and facility automation validation (Siemens, OSIsoft PI, Allen-Bradley platforms).

What tech stack does Kriya Therapeutics use?

Manufacturing and analytics: NONMEM, R, ddPCR, HPLC (assays); OSIsoft PI, DeltaV, Allen-Bradley, Siemens, PLC, SCADA (facility automation); Tulip, MES (manufacturing execution); Streamlit, Shiny, Python (data). Adopting MES integration.