TGF-β targeted therapeutics in preclinical and early-stage development
Keros is a biotech company focused on therapeutics targeting transforming growth factor-beta signaling pathways, currently in preclinical and early clinical stages. The hiring profile is heavily skewed toward research (16 of 30 open roles) and dominated by interns (16 of 30), indicating active scaling of hands-on lab capacity rather than leadership expansion. The pain-point cluster around clinical trial operations, data governance, and GLP/GCP compliance signals a company navigating the transition from discovery into regulated preclinical work.
Notable leadership hires: Medical Director
Keros develops novel therapeutics designed to address disorders linked to dysfunctional TGF-β signaling. The company's active research spans mouse models of kidney fibrosis and neuromuscular disease, in vitro protein assays, and stem cell biology—typical of a preclinical-stage biotech. Current operational focus includes analytical method development, Fc-fusion characterization, and preclinical studies in muscle and bone biology. Headquartered in Lexington, Massachusetts, Keros is a publicly traded company with 51–200 employees, operating across R&D, clinical, quality, manufacturing, and corporate functions.
Keros runs preclinical research on mouse models of kidney fibrosis and neuromuscular diseases, develops in vitro assays for therapeutic proteins, and characterizes Fc-fusion molecules. Active projects also include analytical method development and IP compliance work.
Core lab tools include qPCR, GraphPad Prism, SDS-PAGE, and HPLC for analytical work. Administrative stack: DocuSign, Veeva QualityDocs (regulatory/quality), Microsoft Office, SPSS, and Excel. No adopting or replacing moves listed.
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