Clinical-stage ADC biotech advancing 4 programs in global trials
Duality Biologics is a Shanghai-based ADC (antibody-drug conjugate) company with 4 assets in clinical development and 10+ preclinical candidates. The tech stack—WinNonlin, Monolix, PyTorch, TensorFlow, R, Python, plus LangChain and LangGraph—reveals dual competencies: pharmacokinetic/pharmacodynamic modeling and emerging AI-driven workflows for research acceleration. Active hiring skews heavily research (6 roles) and leadership (7 director/VP/medical director positions), signaling both technical depth in chemistry/biology and scaling pressures on clinical execution.
Notable leadership hires: Medical Director
Duality Biologics develops next-generation ADC therapeutics targeting oncology and autoimmune disease. The company operates from Shanghai and has established multiple proprietary ADC technology platforms with global IP coverage. The pipeline includes 4 programs in international multi-center clinical trials (MRCT) and 10+ preclinical programs. Near-term focus spans dose optimization, formulation bridging, biomarker assay development, and advancement of preclinical assets toward investigational new drug (IND) submissions. The company has signed licensing partnerships with multinational pharma partners globally.
Duality develops ADC therapies for cancer and autoimmune diseases. Current work includes TCE platform development, next-generation ADC platform innovation, pipeline progression to IND submission, dose optimization, drug-drug interaction studies, and biomarker assay development.
Research and development tools: WinNonlin, Monolix, R, Python, PyTorch, TensorFlow. Infrastructure: Git, Docker. AI/ML: LangChain, LangGraph, RAG, Transformer, Claude. Enterprise: SAP, PowerPoint, Excel, NotebookLM.
Shanghai, China. The company was founded in 2020 and currently employs 201–500 people, with all hiring activity concentrated in China.
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